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COP1 interacts with p27 to mediate nuclear export. (A) The Flag-p27 (VPAA) mutant nuclear staining is not diminished in the presence of COP1. 293T cells were co-transfected with either wild-type (wt) or VPAA mutant RFP-p27 and GFP-COP1 and stained with DAPI. (B) Percentages of nuclear p27 signals among GFP-COP1-positive cells in A are shown.
