Skip to main content
. 2015 Sep 14;16(9):22169–22189. doi: 10.3390/ijms160922169

Table 2.

Exon usage and biological relevance of adipocyte-related AS events.

Gene AS Region Adipocyte Isoform Biological Signatures References
mTOR Intron 5 Excluded Promote white adipogenesis [42]
Lipin 1 Exon 7 Included/Excluded Differentiation/Lipid storage [48,51,52]
INSR Exon 11 Included Promote brown adipogenesis [13,62]
MEF2C Alternative 3′ splice site of Exon 10 Distal Promote brown adipogenesis [63]
NcoR Exon 37b Included/Excluded Proliferation/Differentiation [66,67,68,69,70,71,72,73,74,75,76,77]
PKCδ Alternative 5′ splice site of Exon 9 Proximal Promote adipogenesis [30,78,79,80,81,82,83,84,85]
CETP Exon 9 Included Promote lipid metabolism [86,87,88,89,90,91]
RUNX1T1 Exon 6 Included Promote white adipogenesis [54]
ODC Exon 1, 2 and 3 Selection of exon 2 and 3 Promote lipid accumulation [105,106,107]