Table 4.
Morphometric indices for tubular epithelium damage in the kidneys of rats after repeated intraperitoneal injections of NiO or Mn3O4 nanoparticles, together or separately, and of their combination with background oral administration of the BPC (X ± s.e.).
| Groups of Rats Given | Brush Border Loss (% Lengthwise) | Epithelial Desquamation (% Lengthwise) |
|---|---|---|
| Water (control) (4 rats) | 5.44 ± 0.9 | 0.00 ± 0 |
| NiO-NPs (4 rats) | 10.3 ± 1.7 * | 0.48 ± 0.36 |
| Mn3O4-NPs (4 rats) | 9.02 ± 1.17 * | 0.28 ± 0.32 + |
| NiO-NPs + Mn3O4-NPs (4 rats) | 12.33 ± 2.3 * | 2.43 ± 1.0 * |
| NiO-NPs + Mn3O4-NPs + BPC (4 rats) | 7.08 ± 1.7 | 0.00 ± 0 + |
* statistically significant difference from the control group; + from the group given NiO-NPs + Mn3O4-NPs (without the BPC); (p < 0.05 by Student’s t-test with Bonferroni correction).