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. 2015 Sep 18;16(9):22584–22605. doi: 10.3390/ijms160922584

Figure 5.

Figure 5

IL-10 secretion after four and six days of CD3/CD28 stimulation in PBMC of T1D patients compared to healthy controls. Ratio of increase of IL-10 concentrations (expressed as picograms/milliliter (pg/mL) was calculated in CD3/CD28-stimulated over unstimulated supernatants. Graphs show a significant reduction of IL-10 secretion in T1D patients compared to healthy controls, both, after four days (A) (Kolmogorov-Smirnov test p > 0.10; unpaired t test with Welch’s correction p = 0.0275) and six days (B) (Kolmogorov-Smirnov test p < 0.05; Mann Whitney test p = 0.0147) of CD3/CD28 stimulation.