Figure 5.
Accumulated megakaryocyte-erythroid progenitor cells expressing Hoxa5 are partially undergoing apoptosis. (A) Apoptosis analysis of CMP, GMP and MEP in bone marrow of GFP control and Hoxa5-GFP recipient mice 6 months after transplantation. Annexin-V+, PtdIns- cells represent apoptotic cells. Annexin-V+, PI+ cells represent dead cells. Plots from one representative experiment are shown. (B) Statistical analysis of apoptosis of CMP, GMP and MEP (n = 3, **P < 0.01).