CAR and stress-related activity. Individual differences in the CAR (assessed as the increase in cortisol within the first 30 min after awakening, t30–t0) predict stress-related brain activity in a pregenual area of the pACC (T1,21=4.04, p<0.05, FWE-corrected for bilateral pACC, shown at P<0.005 uncorrected for display purposes).