Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Oct 30;13(18):2931–2943. doi: 10.4161/15384101.2014.946869

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 The Author(s). Published with license by Taylor & Francis Group, LLC

© Birgit Steinmetz, Hubert Hackl, Eva Slabáková, Ilse Schwarzinger, Monika Smějová, Andreas Spittler, Itziar Arbesu, Medhat Shehata, Karel Souček, and Rotraud Wieser

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

PMC Copyright notice

Figure 2. — Evi1 and ATRA cooperatively regulate gene expression in HL-60 cells. (A) Immunoblot analysis demonstrating expression of ectopic Evi1 in HL-60_Evi1 cells. (B) Intranuclear staining and flow cytometry showing expression of ectopic Evi1 in HL-60_Evi1 cells on the single cell level. Red, EVI1 antibody; gray, isotype control. (C) Heatmap representing the expression (z-score) of genes whose induction by ATRA was enhanced by, or observed only in the presence of, Evi1 (category 1, CAT1) in HL-60 cells. In this model system, no genes fulfilled the criteria for inclusion into categories 2-4.