Table 3.
SREBP1 and SREBP 2 gene expression in livers of mice with SREBP1c-N overexpression
| Parameter | S1Pf/fLuci | S1Pf/fCre | S1Pf/fCre + N-SREBP1c |
|---|---|---|---|
| Number and sex | 4 males | 4 males | 4 males |
| SREBP1c mRNA %# | 100 ± 14 | 43 ± 9 | 392 ± 42* |
| SREBP2 mRNA %# | 100 ± 27 | 50 ± 5.3 | 88 ± 13* |
Hepatic mRNA levels of SREBP1c and SREBP2 in the experiment presented in Fig. 6e. Each value represents the mean ± the SD of 4 mice. The statistical significance (Student’s t test) between S1Pf/fCre and S1Pf/fCre + N-SREBP1c was calculated. *P < 0.05 #mRNA expression is expressed as a % of the corresponding S1Pf/f Luci value