Table 2. Anatomic and hemodynamic characteristics of the Control and IR rats at the end of the 12th week.
Control | IR | |
---|---|---|
BW (g) | 515±26 | 532±29 |
HW (mg) | 1201±43 | 1679±71* |
HW/BW (mg/g) | 2.33±0.09 | 3.15±0.20* |
Heart rate (beats/min) | 345±21 | 364±25 |
SBP (mmHg) | 109±5 | 142±8* |
MAP (mmHg) | 97±6 | 123±9* |
IR: insulin resistance; HW: heart weight; BW: body weight; SBP: systolic blood pressure; MAP: mean arterial pressure. n = 6 for each group. The values are presented as the means±SE.
*P<0.05 compared with the Control group.
SBP was measured in the conscious state, and MAP and HR were determined under anesthesia.