Table 2.
Factors Associated with Rehospitalization or Death at 1 Year in Univariate Analysis*
| Variable | OR | 95% CI | P Value |
|---|---|---|---|
| Age | 1.05 | 1.01–1.08 | 0.015 |
| Sex (female) | 0.67 | 0.35–1.28 | 0.226 |
| BMI | 0.96 | 0.91–1.02 | 0.164 |
| Lives with (spouse) | 0.56 | 0.27–1.16 | 0.118 |
| MRC dyspnea score | 4.57 | 2.62–7.95 | <0.001 |
| Main diagnosis (ILD) | 1.47 | 0.36–6.03 | 0.589 |
| Smoking (yes) | 0.46 | 0.11–1.87 | 0.280 |
| Pack-years | 1.00 | 0.99–1.01 | 0.608 |
| Long-term oxygen therapy (yes) | 12.36 | 4.53–33.77 | <0.001 |
| Quadriceps strength | 0.96 | 0.92–1.01 | 0.124 |
| Qcsa | 0.34 | 0.17–0.65 | 0.001 |
| ISWT | 1.00 | 0.99–1.00 | 0.077 |
| ESWT | 1.00 | 1.00–1.00 | 0.210 |
| FEV1 on discharge | 0.49 | 0.23–1.05 | 0.066 |
| Total number of comorbidities | 0.87 | 0.69–1.12 | 0.282 |
| Mobility-limiting comorbidity† (yes) | 0.69 | 0.36–1.32 | 0.263 |
| Initial length of hospital stay | 1.06 | 0.99–1.14 | 0.092 |
| Previous hospitalization‡(yes) | 4.82 | 2.42–9.58 | <0.001 |
| Treatment allocation (intervention) | 1.31 | 0.69–2.49 | 0.416 |
Definition of abbreviations: BMI = body mass index; CI = confidence interval; ESWT = endurance shuttle walk test; ILD = interstitial lung disease; ISWT = incremental shuttle walk test; MRC = Medical Research Council; OR = odds ratio; Qcsa = quadriceps cross-sectional area over height squared.
*
ORs are shown for each separate variable. Significant variables are shown in boldface. ORs are per unit increase for continuous variables. For categorical variables, the group for which the OR is shown is provided in parentheses.
†
Defined as significant cardiac disease, musculoskeletal disease, or vascular disease.
‡
Hospitalization in previous 12 months.