Table 2.
Hemorheological and hemodynamic parameters of patients with diabetes with (T2DM-SCT) or without (T2DM) SCT and of healthy individuals with (SCT) or without (CONT) SCT
| T2DM-SCT | T2DM | SCT | CONT | |
|---|---|---|---|---|
| Hct (%) | 40.6 ± 2.3 | 41.3 ± 2.1 | 41.8 ± 2.2 | 40.5 ± 1.3 |
| Blood viscosity (cP) | ||||
| 5.62 s−1 | 11.1 ± 1.0***,† | 10.9 ± 0.8***,† | 10.2 ± 0.8** | 9.2 ± 0.9 |
| 11.25 s−1 | 9.7 ± 1.0***,† | 9.8 ± 0.8***,†† | 8.9 ± 0.6* | 8.2 ± 0.8 |
| 22.5 s−1 | 8.7 ± 0.9***,†† | 8.7 ± 0.6***,††† | 7.9 ± 0.5* | 7.2 ± 0.6 |
| 45 s−1 | 7.7 ± 0.8***,† | 7.6 ± 0.5***,† | 7.1 ± 0.5* | 6.4 ± 0.3 |
| 90 s−1 | 7.0 ± 0.7*** | 6.5 ± 0.4* | 6.5 ± 0.5*** | 5.8 ± 0.4 |
| 225 s−1 | 6.3 ± 0.7***,# | 5.8 ± 0.4*** | 5.9 ± 0.4*** | 4.9 ± 0.4 |
| Plasma viscosity (cP) | 1.8 ± 0.4**,†† | 1.8 ± 0.4**,†† | 1.3 ± 0.3 | 1.4 ± 0.3 |
| Baseline diameter (mm) | ||||
| Systolic | 4.0 ± 0.5 | 4.0 ± 0.5 | 4.0 ± 0.4 | 4.2 ± 0.5 |
| Diastolic | 3.7 ± 0.4 | 3.8 ± 0.5 | 3.8 ± 0.4 | 3.9 ± 0.5 |
| Baseline blood flow (mL/min) | ||||
| Systolic | 331 ± 112 | 310 ± 120 | 299 ± 98 | 292 ± 88 |
| Diastolic | 286 ± 106**,†† | 266 ± 84*,† | 202 ± 40 | 197 ± 53 |
| Baseline shear rate (s−1) | ||||
| Systolic | 504.5 ± 135.5 | 452.0 ± 117.0 | 445.0 ± 120.1 | 386.0 ± 99.8 |
| Diastolic | 156.8 ± 63.3***,† | 142.1 ± 47.8* | 110.3 ± 31.2 | 95.7 ± 25.4 |
| Baseline shear stress (dyn/cm2) | ||||
| Systolic | 26.7 ± 9.5*** | 22.3 ± 6.4 | 23.2 ± 7.1 | 16.6 ± 3.9 |
| Diastolic | 10.5 ± 4.5***,†† | 8.9 ± 2.8* | 7.1 ± 2.0 | 5.6 ± 1.6 |
Data are means ± SD.
*Different from CONT, P < 0.05.
**P < 0.01.
***P < 0.001.
†Different from SCT, P < 0.05.
††P < 0.01.
†††P < 0.001.
#Different from T2DM, P < 0.05.