Table 1.

Expression and β-cell enrichment of miRs discussed

miRs	Human β-cells	Human islets	Mouse islets	Mouse MIN6 cells	β-Cell enrichment
miR-375	5,804,575	2,046,518	636,788	369,695	2
miR-7	670,521	259,457	842,839	423	3
let-7a	668,000	343,033	227,187	4,481	5
miR-148a	389,911	176,002	742,453	15,457	56
miR-26a	389,655	132,411	46,550	25,539	3
miR-182	327,398	152,455	33,286	38,695	10
miR-184	151,568	58,167	56,873	143
miR-30d	111,933	149,301	61,834	12,796	3
miR-200c	60,837	72,125	153,868	1,297	3
miR-21	60,031	284,834	27,077	1,514	5
miR-24	34,032	69,287	58,673	390	6
miR-204	32,817	8,346	890	11	108
miR-200b	22,134	14,969	27,367	2,236	2
miR-30a-5p	21,116	117,912	174,538	9,278	4
miR-16	18,254	10,389	3,215	5,186	3
miR-29a	15,815	13,379	39,338	1,375	3
miR-15a	2,914	1,982	684	89	16
miR-19b	2,081	1,321	56
miR-152	1,656	1,659	44,121	211
miR-29b	1,212	1,500	1,984		3
miR-342	1,017	586	300	449
miR-9	687	2,028	275
miR-96	514	499	500	312	23
miR-15b	442	330	133	149
miR-195	213	516	244		2
miR-34a	190	503	62
miR-199a-3p			168	4
miR-145	49	804	206		2
miR-124a	41	120	17
miR-33a		92	34
miR-338-3p			193	72

MiRs are listed in order of their expression level in human β-cells as assessed by RNA sequencing. Numbers represent read counts in sorted human β-cells (27), intact human islets (27), C57BL/6J mouse islets (19), and MIN6 cells (26). Enrichment in human β-cells in comparison with α-cells was assessed by a quantitative PCR-based miR array; numbers represent fold enrichment (28).