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. 2014 Oct 29;13(23):3742–3749. doi: 10.4161/15384101.2014.965044

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Figure 2. — Enrichment of telomere sequences bound to TRF1 in ChIP-seq experiments. The percentage of 40 or 42-bp raw reads before alignment with mouse genome containing perfect (TTAGGG)₅ or (CCCTAA)₅ repeats is shown for the different samples. In the first experiment, input pool 1 is a combination of equal amounts of input DNA (total DNA before immunoprecipitation) from Trf1^+/+ p53^−/−-Cre and Trf1^Δ/Δ p53^−/−-Cre samples (A). In the second experiment, input pool 2 is a combination of input DNA from wild-type, Terc^−/− G1 and Terc^−/− G3 samples (B).