Figure 11.
kE2F8 is induced by oxidative stress and DNA damage during decidualization. (A) The SOD activity in decidua tissues on day 8 of pregnancy. (B) The SOD activity in stromal cells under in vitro decidualization. The mRNA level of E2f8 in stromal cells treated with H2O2 (C) and Paraquat (D) for the induction of oxidative stress. (E) Western blot of p-H2A.X in mouse uterus from day 7 and 8 of pregnancy. The mRNA of E2f8 in stromal cells treated with UV (F) and CPT (G). (H) Western blot of E2F8 and p-H2A.X in stromal cells treated with CPT.