Table 1.
Clinical characteristics and imaging findings in patients with and without PDPH
All patients | PDPH (n = 23) | No PDPH (n = 57) | P-value* | |
---|---|---|---|---|
Demographics | ||||
Age (years) | 49.4 ± 13.3 | 44.2 ± 12.8 | 51.4 ± 13.1 | 0.027 |
Female patients (%) | 63.8 | 69.6 | 61.4 | 0.492 |
Height (cm) | 163.5 ± 8.9 | 164.5 ± 9.5 | 163.0 ± 8.7 | 0.552 |
Body weight (kg) | 65.2 ± 13.4 | 63.2 ± 12.6 | 66.0 ± 13.8 | 0.404 |
Body-mass index | 24.3 ± 4.4 | 23.2 ± 3.3 | 24.7 ± 4.8 | 0.167 |
Indication for lumbar puncture | ||||
Suspected symptomatic headache | 50% | 52.2% | 49.1% | 0.805 |
Pressure | ||||
Opening pressure (mmH2O) | 160.3 ± 54.4 | 151.6 ± 40.0 | 162.9 ± 58.1 | 0.472 |
Closing pressure (mmH2O) | 113.2 ± 42.0 | 112.3 ± 42.9 | 113.5 ± 42.1 | 0.923 |
Any CSF leakage on HT2W MRM | 67.5% | 100% | 54.4% | <0.001 |
Periradicular leaks | 50% | 95.7% | 31.6% | <0.001 |
Length (seg) | 1.5 ± 2.3 | 3.0 ± 2.5 | 0.9 ± 1.9 | 0.001 |
Cervical (%) | 1.3% | 4.3% | 0% | 0.113 |
Thoracic (%) | 23.8% | 52.2% | 12.3% | <0.001 |
RMax (seg) | 1.8 ± 3.3 | 4.3 ± 4.7 | 0.8 ± 1.7 | 0.002 |
Epidural collections | 41.3% | 69.6% | 29.8% | 0.001 |
Length (seg) | 2.2 ± 4.2 | 5.3 ± 6.1 | 1.0 ± 2.1 | 0.003 |
Cervical (%) | 2.5 | 8.7 | 0 | 0.024 |
Thoracic (%) | 20 | 34.8 | 14.8 | 0.036 |
RMax (seg) | 2.0 ± 4.4 | 4.7 ± 6.7 | 0.9 ± 2.4 | 0.015 |
Retrospinal collections | 37.5% | 52.2% | 31.6% | 0.085 |
HT2W = heavily T2-weighted; seg = segments; RMax = maximum rostral migration. Data are expressed as mean ± standard deviation or percentage. *Comparison between patients with and without PDPH.