Variable	Significance (p-value)	Hazard ratio	95% CI for Exp(B)
			Lower	Upper
Routine follow-up for 5 yr	0.197	0.85	0.67	1.09
Age > 40 yr	< 0.001	0.55	0.46	0.66
Histologic grade I (vs. II/III)	< 0.001	0.34	0.24	0.46
Staging I (vs. II/III)	< 0.001	0.44	0.37	0.54
HR+ and HER2- (vs. the others)	< 0.001	0.70	0.59	0.82

CI, confidence interval; HR, hormone receptor; HER2, human epidermal growth factor receptor 2.