Variable	Significance (p-value)	Hazard ratio	95% CI for Exp(B)
			Lower	Upper
Routine follow-up for 5 yr	< 0.001	0.28	0.22	0.35
Age > 40 yr	< 0.001	0.62	0.49	0.78
Histologic grade I (vs. II/III)	< 0.001	0.17	0.09	0.29
Staging I (vs. II/III)	< 0.001	0.36	0.28	0.47
HR+ and HER2- (vs. others)	< 0.001	0.59	0.48	0.73

CI, confidence interval; HR, hormone receptor; HER2, human epidermal growth factor receptor 2.