Figure 5.
Canonical pathways affected by ubiquitinome alterations in RAS-induced OIS. (A) Ingenuity pathway analysis of proteins with OIS-associated significant fold changes (>3 SD) at ubiquitination sites. Fold changes in ubiquitination sites were adjusted by changes on the protein level. The cut-off for observations included in the analysis was set to a 1.5-fold change. (B) Focus molecules of the affected pathways with respective fold changes at ubiquitination sites.