Table 5.

The association of radiation dose, chemotherapy factors and cardiac clinical factors in the development of pericardial effusion

Dose/factors	Patients, n = 143	Odds ratio	Univariate analysis, 95% confidence interval	p-value
Radiation dose (Gy)
Median (range)	60 (50–60)	–	–	–
=60 Gy	130	2.22	0.58–8.46	0.24
Chemotherapy
High-dose FP	65	–	–	–
Low-dose FP	23	1.12	0.41–3.05	0.83
5-fluorouracil plus nedaplatin regimen	36	1.87	0.81–4.32	0.14
Other	6	1.05	0.18–6.18	0.96
Non	13	2.44	0.73–8.18	0.15
Induction chemotherapy	6	1.64	0.32–8.40	0.56
Hypertension	30	1.29	0.57–2.93	0.54
Atrial fibrillation	6	1.64	0.32–8.40	0.56
Heart failure	2	1.61	0.10–26.30	0.74
Cardiac disease	2	1.61	0.10–26.30	0.74
Diabetes	16	2.26	0.79–6.48	0.13

FP, 5-fluorouracil plus cisplatin regimen.

Radiation dose and chemotherapy were not significant either and cardiac clinical factors were not significant.