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. 2014 Oct 29;13(21):3375–3389. doi: 10.4161/15384101.2014.952183

Figure 1.

Figure 1.

Edelfosine displays selective embryonic lethality without affecting growth or fertility. (A) Shown are growth dynamics of N2 larvae over time when larvae are maintained on NGM plates with or without edelfosine. Each data point represents the mean values of 14 to 69 individual animals ± SD. (B) Percentage of L1 larvae that became adults after 2.7 d on NGM plates with or without edelfosine. n = 427 (control) and n = 155 (edelfosine). Data shown represent mean values ± SD of 3 experiments. (C) Embryonic progeny and oocytes laid by N2 worms during 4 d for worms treated with edelfosine and for untreated worms. Data shown represent mean values for 5 independent worms ± SD. (D) Percentage of surviving embryos (n ≥ 400 per treatment) laid by L3-L4 worms treated with different concentrations of edelfosine using standard NGM plates. Each bar in the histogram represents the mean values ± SD of at least 3 independent experiments.