Table 2. The 17 enriched biological pathways and diseases for 194 MS genes.
| Pathway/Disease Name | Database | p-value | Benjamini-Hochberg corrected p-value |
|---|---|---|---|
| Pathways | |||
| MicroRNAs in cancer | KEGG | 3.16E-17 | 1.94E-13 |
| Platelet degranulation | Reactome | 2.06E-05 | 0.004170147 |
| Role of DCC in regulating apoptosis | Reactome | 2.70E-05 | 0.004714507 |
| Response to elevated platelet cytosolic Ca2+ | Reactome | 3.10E-05 | 0.00494768 |
| inhibition of matrix metalloproteinases | BioCarta | 4.11E-05 | 0.005866484 |
| Extracellular matrix organization | Reactome | 0.0001054 | 0.010318122 |
| TRAIL signaling | Reactome | 0.0001807 | 0.013194457 |
| Dimerization of procaspase-8 | Reactome | 0.0002556 | 0.016503079 |
| Regulation by c-FLIP | Reactome | 0.0002556 | 0.016503079 |
| Caspase-8 activation by cleavage | Reactome | 0.0002556 | 0.016503079 |
| Platelet activation, signaling and aggregation | Reactome | 0.0002928 | 0.017411502 |
| De novo pyrimidine deoxyribonucleotide biosynthesis | PANTHER | 0.0003371 | 0.018942573 |
| p53 signaling pathway | KEGG | 0.0005346 | 0.025033317 |
| p53 pathway | PANTHER | 0.0006532 | 0.028619345 |
| Proteoglycans in cancer | KEGG | 0.0008741 | 0.035273524 |
| Extrinsic pathway for apoptosis | Reactome | 0.001352 | 0.048781856 |
| Death receptor signalling | Reactome | 0.001352 | 0.048781856 |
| Diseases | |||
| Intracranial aneurysm | FunDO | 0.000185 | 0.01334844 |
| Neoplasm metastasis | FunDO | 0.0003232 | 0.018481418 |