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. 2015 Jul 7;14(17):2810–2820. doi: 10.1080/15384101.2015.1068482

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Figure 1. — Posttetraploid progenies (PTs) are chromosomally unstable. (A) Schematic depiction of the experimental strategy. (B, C) SNP array profiles of HCT116, RPE1 and their posttetraploid derivatives. Copy numbers are indicated by colors. The log R represents the copy number; B-allele frequency (BAF) indicates the allele composition: BAF of 0 or 1 represents genotype of AA / A- / BB / B-, respectively; BAF of 0.5 represents AB. (D) Multicolor FISH karyotyping of 2 cells from the HPT2 cell line (number of chromosomes was 72 and 79, respectively). Note the difference in copy number of chromosomes 1, 3, 4, 6, 7, 8, 9, 10, 11, 12, 13, 15, 16, 17, 18 and 20.