Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Oct 21;5:15452. doi: 10.1038/srep15452

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(A) Atomic model (PDB code 1URU) of Drosophila amphiphysin (top). The crescent BAR unit is achieved by dimerization (unit 1 and unit 2, bottom). The amphipathic H0 helix is not visualized, as it is unstructured in the crystallization condition. (B) Fitting of the atomic model shown in (A) to the amphiphysin mediated tube of 280 Å –diameter. The black box highlights the tip portion not visualized by the reconstruction. (C) The density of a section of the 3D reconstruction (left) in comparison to the densities of the amphiphysin atomic model fitted and symmetrized according to the arrangement calculated from the 3D reconstruction. Inner/outer: headgroup density of the inner or outer leaflet. One tip of the BAR is immersed into the acyl chain region according to the rigid body fitting. This part of the reconstruction was not resolved due to the surrounding lipids (boxed in (B)). (D) (Top) The rod-like density connecting the BAR units are marked with a pink bar. (Bottom) A cropped representation of (top) without the pink marker. (E) Representation of the atomic models showing the arrangement of the neighboring BAR units.