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. 2015 Oct 6;12(111):20150703. doi: 10.1098/rsif.2015.0703

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© 2015 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 1. — The number of cholera cases prevented via vaccination with a given set of oral cholera vaccine (OCV) doses when using a minimax strategy compared with several other simple strategies (accept all requests, vaccinate proactively in an endemic setting or accept optimal request assuming perfect knowledge of all future requests). For the minimax strategy (solid line) the decision to fulfil a request is made by comparing the expected cases prevented by the request to the number of cases that would be prevented in an endemic setting (X_min = 7500), which represents the minimum utility of the OCV doses. It is assumed that three requests for vaccine are received in chronological order: the first request will only prevent 3000 cases (open square) so it is rejected, the second request will prevent 10 000 cases and is accepted (solid square), and the third request cannot be accepted because all OCV doses have already been allocated.