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. 2015 Oct 22;5:15501. doi: 10.1038/srep15501

Figure 5. Biomarker specificity for liver injury.

Figure 5

Figure (AD) present circulating miR-122-5p, miR-885-5p, miR-151a-3p and miR-382-5p in APAP-no TOX patients and patients with acute liver injury (ALI) induced by APAP overdose or another aetiology (non-APAP). Figure (EH) present miR-122-5p, miR-885-5p, miR-151a-3p and miR-382-5p in control mice, APAP overdose mice and cisplatin-induced acute kidney injury (AKI) mice. Values represent 2−ΔCt normalised by miR-1287 in human samples and spiked in synthetic miR-39 in mice samples. Statistically significant differences were determined by Wilcoxon matched-pairs signed rank test.