Figure 1.

Effect of diperodon, ATRA, or the diperodon-ATRA combination on the proliferation and differentiation of HL60 cells. Proliferation (A) and differentiation marker expression (CD11b,CD15, CD14, and CD163) by flow cytometry analysis (B–E), of HL60 cells treated with diperodon, ATRA or the diperodon-ATRA combination. Data are reported as mean ± SD of three independent experiments. Statistical significance was calculated using unpaired, 2-tailed Student's t test and considered significant with p < 0 ,05. “NS” indicates not statistically significant differences.