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. 2015 Jan 7;14(7):1090–1102. doi: 10.1080/15384101.2014.1000695

Figure 5.

Figure 5.

Effect of selective inhibitors on caspase 8 and 3 activities in HCC cells exposed to TAX or TAX+TNF for 24 hours. Caspase 8 (A) and 3 (B) activities in cells pretreated with AcDEVDcmk (20 μM) or zIETDfmk (20 μM) for 1 hour, then exposed to 0.1 μM TAX or TAX plus 15 ng/ml TNF for 24 hours. Data (means±SD ) are expressed as nkatal×10–5/mg protein. Significance of the differences vs controls: **P < 0.01 and ***P < 0.001; vs TAX: °P < 0.05, °°P < 0.01 and °°°P < 0.001; vs TAX+TNF: ###P < 0.001.