Figure 6.
76N.TERT cells co-overexpressing Ecd and Ras form tumors upon mammary fat pad implantation in NOD/SCID mice. (A) Tumors were resected. Representative tumor in the mammary gland indicated by an arrow. (B) H & E staining of tumors formed by Ecd+Ras overexpressing cells resected at euthanasia. (C–H) Immunohistochemical analysis of tumor sections for Ecd (C), Ras (D), Vimentin (E), E-cadherin (F), Ki-67 (G), and p63 (H). Pictures were taken at 20X magnification (insets at 40×).