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. 2015 Oct 22;5:15662. doi: 10.1038/srep15662

Figure 5. Expression of genes up-regulated in the human degenerative versus non-degenerative annulus fibrosus.

Figure 5

Real-time RT-PCR data confirm IGFBP3, IFIT3, TFPI and IFIT2 were significantly increased in degenerative annulus fibrosus cells, while PMAIP1, GDF15, MGST1 and IFIT1 were up-regulated with no statistical significance. The data represent fold changes ± standard error. For statistical analysis, a two-tailed t-test was carried out on log2 transformed relative expression data and multiple testing correction was performed according to the method of Benjamini and Hochberg, with 10% false discovery rate considered significant. N = 10 for degenerative samples; N = 8 for non-degenerative samples; *p < 0.05; #p < 0.1 degenerative versus non-degenerative.