Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Oct 22;5:15662. doi: 10.1038/srep15662

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

The schematic generated is representative of the figure produced by IPA ingenuity pathway analysis system that shows the most dysregulated canonical pathway, the IFN signalling pathway, identified by microarray data of human degenerative versus non-degenerative annulus fibrosus. Several genes found dysregulated in degenerative annulus fibrosus are induced or up-regulated through IFNA signalling pathway, such as IFIT1, IFIT2, IFIT3, as well as IGFBP3 and are indicated in pink.