Table 1. Microarray gene expression comparison of human annulus fibrosus cells.
| Symbol | Description | p-value | Log2 fold |
|---|---|---|---|
| IGFBP3 | Insulin-like growth factor binding protein 3 | 0.003 | 2.85 |
| GREM1 | Gremlin 1 | 0.002 | 2.54 |
| PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1 | 0.010 | 2.49 |
| GDF15 | Growth differentiation factor 15 | 0.003 | 2.29 |
| IFIT3 | Interferon-induced protein with tetratricopeptide repeats 3 | 0.004 | 2.03 |
| MGST1 | Microsomal glutathione S-transferase 1 | 0.001 | 2.02 |
| TFPI | Tissue factor pathway inhibitor | 0.002 | 2.01 |
| IFIT1 | Interferon-induced protein with tetratricopeptide repeats 1 | 0.013 | 1.96 |
| IFIT2 | Interferon-induced protein with tetratricopeptide repeats 2 | 0.032 | 1.89 |
| GBP1 | Guanylate binding protein 1, interferon inducible | 0.006 | 1.86 |
| GPR64 | G protein-coupled receptor 64 | 0.022 | −1.59 |
| SOD3 | Superoxide dismutase 3, extracellular | 0.002 | −1.64 |
| CHAD | Chondroadherin | 0.020 | −1.80 |
| LOXL4 | Lysyl oxidase-like 4 | 0.032 | −1.83 |
| LYVE1 | Lymphatic vessel endothelial hyaluronan receptor 1 | 0.011 | −1.85 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.006 | −2.09 |
| IBSP | Integrin-binding sialoprotein | 0.002 | −3.46 |
Significantly differentially expressed genes with p < 0.05, log2 fold cut off ≥±1.5 (degenerative (n = 16) versus non-degenerative (n = 8)).