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. 2014 Oct 30;13(17):2707–2722. doi: 10.4161/15384101.2015.945823

Figure 1.

Figure 1.

(A) Role of CD151 in the branching morphogenesis of mammary glands in mice. (A) Representative images of whole-mounted inguinal mammary glands collected from 6 week old CD151 wild-type (WT) and knock-out (KO) female virgin mice. CD151-targeted FVB mice were used to generate mouse littermates. Scale bar: 1 mm. (B) Changes in ductal lengthand number of secondary and tertiary branches in mammary glands upon CD151 removal (values: mean ± SEM, n = 4). *: P value <0.05. (C) Representative images of whole-mounted mammary glands collected from 7 and 7.5 week old female virgin mice. Scale bar: 1 mm. (D) Typical H&E staining of mammary tissue sections from 7 week old female virgin mice. Scale bar: 500 μm. For (C and D), 2–3 mice per genotype were analyzed at each time point.