Table 1.
CI Analyses of Combination in MCF7 Cells
| 24h |
36h |
48h |
||||
|---|---|---|---|---|---|---|
| 4EG-1(μM) | Cell growth inhibition (%) | CI | Cell growth inhibition (%) | CI | Cell growth inhibition (%) | CI |
| 30 | 17.2 | 0.79 | 18.1 | 0.83 | 21.7 | 0384 |
| 40 | 24.4 | 0.66 | 41.3 | 0.75 | 61.6 | 0.81 |
| 50 | 57.9 | 0.53 | 69.9 | 0.71 | 77.8 | 0.77 |
| 60 | 76.8 | 0.67 | 88.4 | 0.88 | 92.3 | 0.90 |
| 70 | 93.9 | 0.72 | 96.2 | 0.89 | 97.5 | 0.97 |
*
The combination index method is based on the theory described by Chou and Talalay and the computer software of Chou and Martin. (CI < 1 means synergism, CI > 1 means antagonism while CI = 1 means additive.)