Table 2. Statistically significant changed metabolites in TM-4 cells.

Metabolite	VIP	P Value	Fold change
Adenosine	1.781	0.036	0.650
Cis-gondoic acid	1.035	0.027	1.339
Creatine	2.263	0.048	2.001
dTMP	1.500	0.030	0.649
Glutamine	2.424	0.007	2.495
Hydrocortisone	1.035	0.018	0.522
Hydroxylamine	2.040	0.043	1.317
Indolelactate	1.551	0.044	0.545
Malonic acid	1.793	0.033	0.712
N(epsilon)-Trimethyllysine	0.860	0.043	0.792
N-alpha-Acetyl-L-ornithine	1.092	0.032	1.282
Naphthalene	2.004	0.030	1.303
Nicotinic acid	1.048	0.026	1.430
Noradrenaline	2.424	0.027	1.424
O-methylthreonine	0.376	0.026	0.873
Pantothenic acid	1.717	0.024	1.200
Spermidine	2.039	0.036	0.367
Thymidine	1.770	0.020	0.356
Uracil	2.048	0.019	2.074