Figure 4.

Schematic view of the interactions between statins and CTLD. The 2D depictions show hydrogen bonds as black dashed lines between the interaction partners on either side. Hydrophobic interactions are illustrated as smooth green contour lines between the respective amino acids and the ligand. Stacking interactions are indicated by green dashed lines between filled green circles. The ligand itself is drawn utilizing the 2D draw engine according to chemical drawing conventions. This image has been produced using the PoseView software.⁶⁴