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. 2015 Jan 7;6(1):15–18. doi: 10.1080/19491034.2015.1004258

Figure 1.

Figure 1.

Involvement of ubiquitous TFs in the transcriptional regulation of cell differentiation. The main concepts discussed in the manuscript are summarized (see text for details). The absence or presence of histone modifications that characterize active enhancers (H3K4me1 and H3K27ac) is indicated together with DNA methylation (5mC) and DNA hydroxymethylation (5hmC). H3K4me1, monomethylation of histone H3 lysine 4; H3K27ac, acetylation of histone H3 lysine 27; 5mC, 5-methylcytosine; 5hmC, 5-hydroxymethylcytosine.