Table 3.

Comparison of bacterial genera significantly (P<0.05) over or under represented in tumor adjacent tissues from the US and Spain. Numbers represent the relative abundance (%) ± standard deviation. Shaded cells indicate higher relative abundance.

Phyla	Genera	US	Spain	P-value
Actinobacteria	Propionibacterium	0.1±0.2	0.02±0.09	0.0452
	f_Coriobacteriaceae	0.02±0.07	0.09±0.19	0.0096
	Bifidobacterium	0.0±0.0	0.03±0.14	0.0059
	Collinsella	0.1±0.1	1.27±1.83	0.0001
	Slackia	0.008±0.02	0.05±0.13	0.0426
Bacteroidetes	Bacteroides	39.9±21.4	27.1±17.6	0.0469
	Butyricimonas	0.06±0.15	0.16±0.25	0.0054
	f_[Barnesiellaceae]	0.38±0.72	1.39±2.46	0.0075
	Paraprevotella	0.07±0.31	0.17±0.35	0.0411
	f_Rikenellaceae	0.37±0.61	1.30±1.96	0.0215
Firmicutes	Selenomonas	0.6±1.9	0.0±0.0	0.0037
	Geobacillus	0.3±0.6	0.0±0.0	0.0008
	Schwartzia	0.3±1.0	0.0±0.0	0.0067
	Bulleidia	0.5±0.8	0.1±0.2	0.0224
	Lachnospira	0.002±0.01	0.07±0.21	0.0123
	Anaerostipes	0.0±0.0	0.01±0.04	0.0059
	Dorea	0.27±0.44	1.30±1.61	0.0355
	02d06	0.0±0.0	0.01±0.04	0.0233
	cc_115	0.0±0.0	0.01±0.02	0.0059
	f_Lachnospiraceae_Other	1.93±2.37	4.65±5.44	0.0328
	Turicibacter	0.0±0.0	0.02±0.09	0.0118
	f_Clostridiaceae_Other	0.01±0.05	0.35±1.43	0.0032
	Coprococcus	0.09±0.12	1.41±2.58	0.0002
	Lactobacillus	0.03±0.13	0.43±1.00	0.0143
	Epulopiscium	0.0±0.0	0.08±0.23	0.0454
	f_Christensenellaceae	0.008±0.02	0.31±0.88	0.0147
	f_Ruminococcaceae	1.61±1.63	4.93±4.95	0.0076
Fusobacteria	Fusobacterium	9.4±19.6	1.6±3.9	0.0017
	Leptotrichia	0.3±0.6	0.0±0.0	0.0194
	Cetobacterium	0.0±0.0	0.10±0.40	0.0233
Proteobacteria	Campylobacter	0.5±2.0	0.0±0.0	0.0122
	Ralstonia	2.1±4.2	0.9±4.3	<.0001
	f_Bradyrhizobiaceae	0.0±0.0	0.16±0.77	0.0454
	Acidocella	0.0±0.0	0.08±0.2	0.0233
	Stenotrophomonas	0.0±0.0	0.007±0.01	0.0454
	Bilophila	0.0±0.0	0.02±0.04	0.0014
Synergistetes	TG5	0.3±0.7	0.0±0.0	0.0011