Table 2.
Distribution of genotypes and allele frequencies of IL-10 (-1082 A/G), IL-12p40 1188A/C, and IL-13+2044G/A in glioma patients and control subjects.
| Variables | Cases (N=96) | Control (N=40) | P-value | OR (95%CI) |
|---|---|---|---|---|
| IL-10 (-1082 AlG) | ||||
| AA | 72 (75%) | 25 (62.5%) | 0.126 | 1.0 |
| AG | 22 (22.93%) | 11 (27.5%) | 0.051 | 0.174 (0.030-1.006) |
| GG | 2 (2.07%) | 4 (10%) | 0.141 | 0.250 (0.039-1.582) |
| Alleles | ||||
| A | 166 (86.46%) | 61 (76.25%) | 1.0 | |
| G | 26 (13.54%) | 22 (23.75%) | 0.039 | 0.503 (0.260-0.973) |
| IL-12p40 1188A/C) | ||||
| AA | 70(72.92%) | 26 (65%) | 0.633 | 1.0 |
| AC | 23 (23.96%) | 12 (30%) | 0.534 | 0.557 (0.088-3.525) |
| CC | 3 (3.13%) | 2 (5%) | 0.802 | 0.783 (0.115-5.341) |
| Alleles | ||||
| A | 163 (84.9%) | 64 (80%) | 1.0 | |
| C | 29 (15.1%) | 16(20%) | 0.322 | 0.712(0.362-1.398) |
| IL-13 +2044G/A | ||||
| GG | 86(89.58%) | 19 (47.5%) | 0.001 | 1.0 |
| GA | 9 (9.37%) | 13 (32.5%) | 0.001 | 0.028(0.003-0.234) |
| AA | 1 (1.04%) | 8 (20%) | 0.135 | 0.181(0.019-1.706) |
| Allele | ||||
| G | 181 (94.27%) | 51 (63.75%) | 1.0 | |
| A | 11 (5.73%) | 29 (36.25%) | 0.001 | 0.107(0.050-0.229) |