Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jan 20;6(1):40–54. doi: 10.1080/19491034.2015.1004260

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 The Author(s). Published with license by Taylor & Francis Group, LLC

© Michal Schwartz, Anna Travesa, Steven W Martell, and Douglass J Forbes

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

PMC Copyright notice

Figure 8. — A schematic summary of the recruitment and rim localization results for each LacI-CFP-Nup tested. The individual LacI-tagged Nup construct transfected (outlined in red) is indicated above each drawing. Endogenous nucleoporins tested that were recruited to the LacI-Nup/LacO array are shown above the dotted line, while the non-recruited Nups are shown below the dotted line. Nups belonging to the same subcomplex are in the same color (and correlate with the subcomplexes in Fig. 1A). Rim localization of the LacI-Nup/LacO array (% of cells) is denoted by close proximity of the recruited nucleoporins to the double nuclear membrane lines, and also by the % of cells that showed rim localization of the array (RIM: %). Double headed arrows indicate the Nups where the LacI-Nup/LacO array was found adjacent to the membranes, but in lesser percentages. A number of LacI-Nup/LacO arrays (sPom121, Nup214, Nup58, Nup85, and Nup98) showed essentially no rim localization. Red squares denote the members of the 2 subcomplexes that are able to initiate both extensive Nup recruitment to the array and rim localization of the array.