Table 2.
Cell cycle profiles; DNA content was determined by propidium iodide staining of fixed cells and flow cytometric analysis; results are displayed as % of cells (mean ± SEM) on three different donors 24 h after incubation with a 10 nM concentration of PM01215 and PM02781
| G1 phase | S phase | G2 phase | |
|---|---|---|---|
| control | 42.3 ± 2.5 | 14.9 ± 1.4 | 40.3 ± 1.4 |
| PM01215 | 61.1 ± 1.7* | 3.7 ± 1.0* | 34.1 ± 2.4* |
| PM 02781 | 61.8 ± 1.0* | 3.4 ± 0.8* | 33.5 ± 1.7* |
*Indicate p values < 0.05