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. 2015 Apr 22;6(2):120–130. doi: 10.1080/19490976.2015.1023494

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© 2015 The Author(s). Published with license by Taylor & Francis Group, LLC

© Almut Heinken and Ines Thiele

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 1. — Overview of the study design, including the modeling framework, description of included organisms, main constructed host-microbe models and implemented dietary regimes. Examples of the types of exchange reactions that were optimized individually (4679 in total) are also presented. CHO = carbohydrate; Mets = metabolites; [c] = cytoplasm; [e] = extracellular space; [u] = lumen; [x] = peroxisome; [n] = nucleus; [l] = lysosome; [g] = Golgi apparatus; [m] = mitochondrion; [r] = endoplasmic reticulum.