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. 2015 Feb 18;11(11):1335–1339. doi: 10.1080/15476286.2014.996459

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© 2014 The Author(s). Published with license by Taylor & Francis Group, LLC

© Andreas Pircher, Jennifer Gebetsberger, and Norbert Polacek

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 1. — Functional consequences of ncRNA-ribosome interactions. Short or long rancRNAs can target ribosomes (dark gray) either as naked molecules or as RNPs (light gray). As a consequence global (e.g., the yeast TRM10 mRNA-derived 18-mer ncRNA)²⁴ or mRNA-specific translation regulation can occur. Loading ribosomes on ncRNAs can also affect the cellular stability and/or localization of rancRNAs (ref. 19 and references therein). Size and line thickness of the arrows on the right correspond to experimentally supported (thick and solid), predicted (thin and solid), or in principle possible (dotted) rancRNA functions.