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Liver histology of patient 4 (13 mo after occurrence of cholestasis). A: Portal inflammation, severe cholestasis with bile thrombi, HE (20x); B: Lymphocytic infiltration of a small bile duct (arrow). Periodic acid Schiff’s reaction after treatment with diastase (100x); C: Immunostaining for cytokeratin 7. Regenerative bile duct proliferations show a strong expression of cytokeratin 7 (25x).
