Table 2.
Correlation between soluble ICAM-1 concentrations and clinicopathologic factors in colorectal cancer
Factors | n | ICAM-1 (mean±SD, μg/L) | χ2 | P |
Clinical staging | ||||
Dukes A1 | 3 | 352.63 ± 61.82a | ||
Dukes A2,3 | 6 | 491.17 ± 86.36 | 2.88 < 0.05 | |
Dukes B | 21 | 496.82 ± 93.04d | 0.18 > 0.05 | |
Dukes C and D | 26 | 743.68 ± 113.74 | 12.38 < 0.001 | |
Grade of differentiation | ||||
Highly differentiated | 22 | 410.23 ± 67.47b | ||
Differentiated | 24 | 486.53 ± 103.64d | 4.08 < 0.01 | |
Poorly differentiated | 10 | 736.49 ± 121.967 | 10.48 < 0.001 | |
Metastasis | ||||
Liver | 3 | 769.19 ± 127.32 | ||
Lymph node positive | 23 | 756.25 ± 125.57d | 0.32 > 0.05 | |
Lymph node negative | 30 | 445.62 ± 69.18 | 16.98 < 0.001 |
P < 0.05, Dukes A1 vs Dukes A2,3;
P < 0.01, highly differentiated vs differentiated;
P < 0.001, Dukes B vs Dukes C and D; Differentiated vs poorly differentiated; lymph node positive vs lymph node negative.