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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: J Urol. 2015 Apr 23;194(5):1463–1472. doi: 10.1016/j.juro.2015.04.078

Figure 4. Recovery following release of partial UUO in wild-type and Os/+ mice.

Figure 4

A. Comparison of wild-type and Os/+ kidneys. Median sagittal sections (Lotus tetragonolobus staining) of kidneys from 42-day-old animals. B. Details of cortical structure from the same UUO and UUO/R kidneys. In the wild-type mice, staining of Bowman's capsule with Lotus lectin (indicated by arrowheads), an indicator of intact nephrons, is superior to the Os/+ equivalents. In addition, release of ureteral obstruction results in a greater incidence of capsule lectin positivity in the wild-type, but not in the Os/+ (also see Fig. 5E). Persistently obstructed kidneys contain groups of crowded glomeruli with no Lotus lectin staining in their capsules (*). Scale bar in B = 250 μm and applies to all panels.