Table 4.

Prevalence of NP carriage of OM pathogens in NP-swabbed children, by vaccination group

	PCV7		PHiD-CV10		Absolute Risk Difference	P value
					[95 % CI]
	n/N	%	n/N	%
NP carriage
NTHi	284/420	68 %	322/440	73 %	6 %	0.07
					[−0.5 to 12]
Spn	321/420	76 %	359/440	82 %	5 %	0.06
					[−0.2 to 11]
Mcat	202/420	48 %	189/438	43 %	−5 %	0.15
					[−12 to 2]
Sa	136/420	32 %	94/440	21 %	−11 %	0.0003
					[−17 to −5]
Combination NP carriage categories
Spn and NTHi	267/420	64 %	297/440	68 %	4 %	0.23
					[−2 to 10]
Spn or NTHi	361/420	86 %	400/440	91 %	5 %	0.02
					[0.6 to 9]
PCV7 types	38/319	12 %	31/372	8 %	−4 %	0.12
					[−8 to1]
PCV13 types	92/319	29 %	77/372	21 %	−8 %	0.01
					[−15 to −2]
Serotypesb	16Fcd(12 %) 19Acd(10 %) 11Acde 23Bcde 6Cc = 19Fde 23Fcde = 6Aa = 10Ad 33F		16Fd(14 %) 19Ade(8 %) 11Ade 10Ad 6Cc 15Ade 23Fcde 21c 23Bd 35F
	Non-mixed PCV schedules
NP carriage	333a		314
NTHi	225/332	68 %	230/314	73 %	5 %	0.13
					[−2 to 12]
Spn	253/332	76 %	259/314	82 %	6 %	0.05
					[0 to 12]
Mcat	172/332	52 %	127/313	41 %	−11 %	0.004
					[−19 to −4]
Sa	105/332	32 %	70/314	22 %	−9 %	0.008
					[−16 to −2]

^a125 children in the PCV7-only group had also received PPV23

^bStrains within serotypes that are:

^c Azithromycin non-susceptible (MIC > 0.5 mg/L)

^d Penicillin non-susceptible (MIC > 0.06 mg/L)

^e Non-susceptible to both