Figure 5.

hUTP24 protein is associated with homologs of the yeast SSU processome subunits and other pre-rRNA processing factors in human cells. Wild-type (top) and mutant hUTP24 (bottom) were purified as C-terminal fusions with an eGFP-tag. Proteins co-purifying with the bait were analyzed by mass spectrometry and the results were compared to the parallel purification, carried out using the unmodified parental cell line. For a more detailed description of the graphs and data analysis refer to Figure 4.