TABLE 1.
180-Day Survival among All Treatment Groups of WTLI (14.6 Gy) and Sham-WTLI (0 Gy) CBA/J Female Mice
| Treatment group | Number of decedents/total | Percentage lethality | Mean survival time (days) | Median survival time (days) (25–75th percentile) |
|---|---|---|---|---|
| Sham WTLI (all groups)a | 1/60 | 1.7% | 180 ± 0.4 | 180 (180–180) |
| WTLI alone | 18/20 | 90% | 116 ± 5.0 | 111 (107–112) |
| WTLI-vehicle | 15/19 | 79% | 124 ± 7.3 | 108 (101–141) |
| WTLI-AEOL 10150, 5 mg/kg | 16/19 | 84% | 123 ± 6.1 | 112 (106–124) |
| WTLI-AEOL 10150, 10 mg/kg | 16/19 | 84% | 122 ± 6.2 | 111 (109–121) |
| WTLI-AEOL 10150, 25 mg/kg | 12/20 | 60% | 138 ± 8.0 | 120 (106–180) |
| WTLI-AEOL 10150, 40 mg/kg | 14/20 | 70% | 135 ± 7.0 | 120 (110–180) |
a
Sham WTLI (no treatment, treatment with vehicle or treatment with AEOL 10150).