Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Feb 12;6(2):93–101. doi: 10.1080/19491034.2015.1004941

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 The Author(s). Published with license by Taylor & Francis Group, LLC

© Jana Link, Daniel Jahn, and Manfred Alsheimer

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

PMC Copyright notice

Figure 2. — Meiotic LINC complexes of common model organisms. Meiotic LINC complexes of the different model organisms are all composed of specialized SUN-KASH protein bridges that are used to connect meiotic telomeres to the cytoskeleton. It requires unique adaptor proteins responsible to connect the chromosome ends to the nuclear domain of the SUN protein. These adaptor proteins are highly diverged, species-specific, most likely analogous proteins with similar function. The KASH component of meiotic LINC complexes in most cases interact with microtubule-associated motor proteins. The only described exception refers to S. cerevisiae, in which Csm4 likely links to the actin cytoskeleton.