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. 2015 Jan 23;11(12):1568–1585. doi: 10.4161/15476286.2014.992280

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© 2014 The Author(s). Published with license by Taylor & Francis Group, LLC

© Kirk W Gaston and Patrick A Limbach

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 4. — Information obtained by LC-MS/MS of multiplexed isotope RNA labeling, displayed for m⁵U as a typical ubiquitous modification. Note that the spectrum is an overlay of 3 consecutive injections. Reproduced from Ref. (26) with permission from The Royal Society of Chemistry.